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Restorative Neurology

Our restorative neurology research is centred on the functional recovery of patients after neurological illness or injury including Parkinson’s disease and multiple sclerosis.

Perron Institute’s Centre for Restorative Neurology is a new initiative under the research team. The centre is the first of its kind in Australia and works towards the goal of developing multidisciplinary programs targeted at promoting recovery and functional improvement in neurological patients.

Neurological disorders are one of the leading causes of disability in Australia. In spite of advances in prevention and acute care, a large proportion of patients with cerebrovascular, inflammatory and neurodegenerative disorders are left with significant deficits.

Research Focus

Led by Clinical Professor Soumya Ghosh and Professor Frank Mastaglia AM our Restorative Neurology Group’s research is multidisciplinary and uses state-of-the-art methodologies, including balance assessment and therapy, pulmonary function and therapy and non-invasive brain stimulation. As recovery from neural injury is thought to occur through processes of ‘relearning’ and ‘neuroplasticity’, newer techniques are being increasingly trialled to hasten this relearning process and improve outcomes.

The group uses non-invasive brain stimulation to study the pathophysiology of cerebral dysfunction in Parkinson’s disease (PD) and multiple sclerosis (MS). In clinical trials, our team investigates the use of new therapeutic options provided by non-invasive brain stimulation in neurological disorders and investigate the neural mechanisms of physical therapy in promoting neuroplasticity. We are currently investigating cortical reorganisation in MS and the use of non-invasive brain stimulation to promote neuroplasticity and as a potential biomarker in MS.

We investigate the pulmonary function and the effects of respiratory muscle strength training in patients with Parkinson’s Disease. Current studies are focusing on identifying determinants of pulmonary dysfunction in PD and its effects on balance and exercise, speech and swallowing, and sleep in PD.  The effects of inspiratory muscle training in improving pulmonary function and balance are being studied in a randomised controlled trial. To maintain quality patient and control data our team are creating a Parkinson’s biobank and Parkinson’s Diseases Registry for future researchers and research methods.


  • 2021 Member of the Order of Australia (Prof Frank Mastaglia)

Movement Disorder Clinic

The Movement Disorders Clinics at the Perron Institute provide management and treatment for people with a movement disorder.

Learn more about Movement Disorder Clinic

Multiple Sclerosis Clinics

Multiple Sclerosis Clinics provide services for the accurate diagnosis and effective treatment for individuals with multiple sclerosis (MS) and other neuroimmunological disorders of the central nervous system (CNS).

Learn more about Multiple Sclerosis Clinics

Your donation will help us find answers for people with neurological disorders and give them hope.


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