Research shaping
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Specialist clinics
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The Perron Institute, formerly known as the Western Australian Neuroscience Research Institute, is a medical research institute focusing on neurological conditions. It brings together a dedicated group of researchers and clinicians, many pre-eminent in their fields.

Perron Institute Medical Research

The Perron Institute, formerly the Western Australian Neuroscience Research Institute, is a medical research institute focusing on neurological conditions. It brings together a dedicated group of researchers and clinicians, many pre-eminent in their fields.

The Perron Institute has a long tradition spread over 35 years of scientific innovation and discovery. This has led to major breakthroughs in our understanding of the origins of neurological disorders and provided insights into the diagnosis and treatment of this debilitating group of diseases. The Perron Institute continues to inspire, training the next generation of researchers though the supervision of graduate and postgraduate students.

The Perron Institute’s research is grouped into the following themes:

  • Genetic Therapies – which includes Molecular Therapies – including US FDA approved Duchenne muscular dystrophy research, Nucleic Acid Therapeutics and Motor Neurone Disease Research;
  • Molecular Neurobiology – which includes Stroke research;
  • Clinical Research – which includes research on conditions such as multiple sclerosis (MS) and myositis;
  • Rehabilitation – which includes Restorative Neurology and Psychology Research; and
  • Neuropathology.

Research

MOLECULAR THERAPIES RESEARCH

The Perron Institute’s Molecular Therapies Research is led by Professors Steve Wilton and Sue Fletcher has a long history of cutting-edge research on novel genetic therapies for neuromuscular disorders, particularly Duchenne muscular dystrophy. More

NUCLEIC ACID THERAPEUTICS RESEARCH

This research is focused on novel functional nucleic acid-based biotechnologies for developing target–specific therapies for neurological diseases, inherited/genetic disorders, and solid cancers. More

MOTOR NEURONE DISEASE RESEARCH

Motor Neurone Disease Genetics and Therapeutics Research at the Perron Institute, lead by Professor Anthony Akkari, aims to identify genetic mechanisms and mutations in neurological conditions, particularly motor neurone disease (MND), with the aim of developing personalised treatments. more

STROKE RESEARCH

The objective of the Perron Institute’s Stroke Research led by Adjunct Associate Professor Bruno Meloni and Clinical Professor Neville Knuckey is to develop treatments to minimise brain damage after stroke and cerebral ischaemia. More

DEMYELINATING DISEASES RESEARCH

Demyelinating Diseases Research is dedicated to investigating the causes of multiple sclerosis (MS) and improving the treatment and management of those suffering from MS and related diseases. More

MYOSITIS RESEARCH

Myositis Research has a longstanding interest in the investigation of clinical, genetic and immunological aspects of the inflammatory myopathies (IBM), with a particular focus on inclusion body myositis, the most common muscle disease associated with aging. More

RESTORATIVE NEUROLOGY RESEARCH

The Centre for Restorative Neurology is an initiative focusing on research to improve functional recovery of patients after neurological illness or injury (including stroke, head injury, Parkinson’s disease and multiple sclerosis). Led by Clinical Professor Soumya Ghosh, this research is multidisciplinary and uses state-of-the-art methodologies, including robotic arm therapy, balance assessment and therapy, cognitive assessment and therapy and non-invasive brain stimulation. More

CLINICAL PSYCHOLOGY RESEARCH

Research in clinical psychology is a developing field of importance to a range of neurological diseases. With research interests in neuroplasticity, neurorehabilitation and the use of holistic biopsychosocial individual and group therapeutic programs, the Clinical Psychology Research Group led by A/Professor Michelle Byrnes undertakes research on individuals with a range of neurological disorders, including stroke, spinal cord injury, multiple sclerosis and Parkinson’s disease. More

NEUROPATHOLOGY RESEARCH

Emeritus Professor Byron A Kakulas AO, Founding Director, continues his neuropathological research in the areas of restorative neurology of spinal cord injuries, Alzheimer’s disease and ALS (motor neurone disease). More

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