Nucleic Acid Therapeutics Research

Chakravarthy M, Al Shamaileh H, Huang H, Tannenberg RK, Chen S, Worrall S, Dodd PR, Veedu RN* (2018) Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitro. Chemical Communication 54: 4593-4596.

Kokil G, Veedu RN, Le BT, Ramm G, and Parekh H (2018). Self-assembling asymmetric peptide-dendrimer micelles – a platform for effective and versatile in vitro nucleic acid delivery. Scientific Reports. doi:10.1038/s41598-018-22902-9

Macdonald J, Henri J, Roy K, Hays E, Bauer M, Veedu RN, Pouliot N, and Shigdar S (2018). EpCAM Immunotherapy versus Specific Targeted Delivery of Drugs. Cancers. DOI: 10.3390/cancers10010019

Nucleic Acid-Based Theranostics for Tackling Alzheimer’s Disease. Chakravarthy M, Chen S, Dodd PR, Veedu RN (2017) Theranostics, 7, 3933-3947. doi:10.7150/thno.21529

Rational design of short locked nucleic acid-modified 2’-O-methyl antisense oligonucleotides for efficient exon-skipping in vitro. Le BT, Adams AM, Fletcher S, Wilton SD, and Veedu RN (2017) Molecular Therapy Nucleic Acids, 9, 155–161. doi: 10.1016/j.omtn.2017.09.002

Nucleobase-modified antisense oligonucleotides containing 5-(phenyltriazol)-2’-deoxyuridines nucleotides induce exon-skipping in vitro. Le BT, Hornum M, Sharma PK, Nielsen P, Veedu RN (2017) RSC Advances, 7, 54542-54545. DOI: 10.1039/C7RA10964D

Construction of a bivalent thrombin binding aptamer and its antidote with improved properties. Hughes Q, Le BT, Gilmore G, Baker R, Veedu RN (2017) Molecules, 22(10), 1770. DOI: 10.3390/molecules22101770

Chakravarthy M, Chen S, Dodd PR, Veedu RN (2017) Nucleic Acid-Based Theranostics for Tackling Alzheimer’s Disease. Theranostics, 7, 3933-3947. doi:10.7150/thno.21529 [Rank: Q1; IF = 8.712]

Hughes Q, Le BT, Gilmore G, Baker R, Veedu RN (2017) Construction of a bivalent thrombin binding aptamer and its antidote with improved properties. Molecules, 22(10), 1770. DOI: 10.3390/molecules22101770 [Rank: Q1; MDPI]

Le BT, Murayama K, Shabanpoor F, Asanuma H and Veedu RN (2017) Antisense oligonucleotide modified with serinol nucleic acid (SNA) induces exon skipping in mdx myotubes. RSC Advances, (2017) 10, 34049-34052. DOI: 10.1039/C7RA06091B