Stroke research sub-category

MacDougall G, Anderton RS, Mastaglia FL, Knuckey NW, Meloni BP. Proteomic analysis of cortical neuronal cultures treated with poly-arginine peptide-18 (R18) and exposed to glutamic acid excitotoxicity. Mol Brain. 2019 Jul 17;12(1):66. doi: 10.1186/s13041-019-0486-8.

Yuan J, Meloni BP, Shi T, Bonser A, Papadimitriou JM, Mastaglia FL, Zhang C, Zheng M, Gao J. The Potential Influence of Bone-derived Modulators on the Progression of Alzheimer’s Disease. Journal of Alzheimer’s Disease. 2019 Mar 22:1-2. doi: 10.3233/JAD-181249

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. (2018). Assessment of therapeutic window for poly-arginine-18D (R18D) in a P7 rat model of perinatal hypoxic-ischaemic encephalopathy. Journal of Neuroscience Research. In press.

Stroke Research

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. (2018). Review: Perinatal hypoxic-ischaemic encephalopathy and neuroprotective peptide therapies: a case for cationic arginine-rich peptides (CARPs). Brain Sciences. In press.

Comparison of neuroprotective efficacy of poly-arginine R18 and R18D (D-enantiomer) peptides following permanent middle cerebral artery occlusion in the Wistar rat and in vitro toxicity studies. Milani D, Bakeberg MC, Cross JL, Clark VW, Anderton, RS, Blacker DJ, Knuckey NW, Meloni BP (2018). PlosOne 13(3): e0193884. https://doi.org/10.1371/journal.pone.0193884

Adam B. Edwards, Jane L. Cross, Ryan S. Anderton, Neville W. Knuckey and Bruno P. Meloni. Poly-arginine R18 and R18D (D-enantiomer) peptides reduce infarct volume and improves behavioural outcomes following perinatal hypoxic-ischaemic encephalopathy in the P7 rat. Molecular Brain (2018) 11:8. doi.org/10.1186/s13041-018-0352-0

MacDougall, G., Anderton, R.S., Mastaglia, F.L., Knuckey, N.W., Meloni, B.P. Mitochondria and Neuroprotection in Stroke: Cationic Arginine-Rich Peptides (CARPs) as a Novel Class of Mitochandria-Targeted Neuroprotective Therapeutics. 2018, Neurobiology of Disease; doi.org/10.1016/j.nbd.2018.09.010

Neuroprotective efficacy of R18 poly-arginine and NA-1 (TAT-NR2B9c) peptides following transient middle cerebral artery occlusion in the rat. Milani, D, Cross, JL, Anderton, RS, Blacker, DJ, Knuckey, NW, Meloni, BP 2017 Neuroscience Research 114:9-15

Characterisation of neuroprotective efficacy of modified poly-arginine-9 (R9) peptides in neuronal glutamic acid excitotoxicity model. Edwards AB, Cross JL, Anderton RS, Knuckey NW, Meloni BP 2017 Mol Cell Biochem 426:75-85

Assessment of R18, COG1410, and APP96-110 in excitotoxicity and traumatic brain injury. Chiu LS, Anderton RS, Cross JL, Clark VW, Edwards AB, Knuckey NW, Meloni BP. 2017 Translational Neuroscience 15; 8:147-157