Dr Athanasios Gaitatzis joined the Perron Institute as a Consultant Neurologist and started his Epilepsy Clinic in early 2016. In late 2017, Dr Gaitatzis started a specialist Epilepsy and Pregnancy clinic, the first of its kind in Australia. He is also a Consultant in the Neurology Department at Sir Charles Gairdner Hospital. His Perron Institute Clinics are focused on the care of people with refractory (or drug-resistant) epilepsy, complex epilepsy (in people with neurodevelopmental or psychiatric comorbidities), and epilepsy in women (dealing with preconception counselling, pregnancy and breastfeeding issues).

Investigation of poly-arginine peptide neuroprotective mechanisms using an in vitro neurotrauma injury model’. Meloni B, Knuckey N, Chiu L, Anderton R. $100,000. Neurotrauma Research Program.

MacDougall G, Anderton RS, Mastaglia FL, Knuckey NW, Meloni BP. Proteomic analysis of cortical neuronal cultures treated with poly-arginine peptide-18 (R18) and exposed to glutamic acid excitotoxicity. Mol Brain. 2019 Jul 17;12(1):66. doi: 10.1186/s13041-019-0486-8.

Yuan J, Meloni BP, Shi T, Bonser A, Papadimitriou JM, Mastaglia FL, Zhang C, Zheng M, Gao J. The Potential Influence of Bone-derived Modulators on the Progression of Alzheimer’s Disease. Journal of Alzheimer’s Disease. 2019 Mar 22:1-2. doi: 10.3233/JAD-181249

Clinical Professor Neville Knuckey is the head of Stroke Research at the Perron Institute.

Clinical Professor Knuckey completed medicine at the University of Western Australia, then trained in Neurosurgery in Western Australia. He completed Neurosurgical Fellowships at The Johns Hopkins and Brown University in the USA.

Adam Edwards

Adam Edwards is a Postdoctoral Research Officer in the area of Stroke Research at the Perron Institute.

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. (2018). Assessment of therapeutic window for poly-arginine-18D (R18D) in a P7 rat model of perinatal hypoxic-ischaemic encephalopathy. Journal of Neuroscience Research. In press.

Stroke Research

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. (2018). Review: Perinatal hypoxic-ischaemic encephalopathy and neuroprotective peptide therapies: a case for cationic arginine-rich peptides (CARPs). Brain Sciences. In press.

Comparison of neuroprotective efficacy of poly-arginine R18 and R18D (D-enantiomer) peptides following permanent middle cerebral artery occlusion in the Wistar rat and in vitro toxicity studies. Milani D, Bakeberg MC, Cross JL, Clark VW, Anderton, RS, Blacker DJ, Knuckey NW, Meloni BP (2018). PlosOne 13(3): e0193884. https://doi.org/10.1371/journal.pone.0193884

Adam B. Edwards, Jane L. Cross, Ryan S. Anderton, Neville W. Knuckey and Bruno P. Meloni. Poly-arginine R18 and R18D (D-enantiomer) peptides reduce infarct volume and improves behavioural outcomes following perinatal hypoxic-ischaemic encephalopathy in the P7 rat. Molecular Brain (2018) 11:8. doi.org/10.1186/s13041-018-0352-0